Artichoke Spinach Grilled Cheese

Featured in: Cozy Eats

This artichoke spinach grilled cheese combines creamy spinach-artichoke dip with melted cheeses between golden sourdough slices. Mix cream cheese, mozzarella, Monterey Jack, and Parmesan with fresh spinach, artichoke hearts, garlic, and seasonings. Spread onto bread, butter the outside, and griddle until golden brown and cheese melts perfectly.

Ready in just 25 minutes, this vegetarian sandwich serves 4 and pairs beautifully with tomato soup or a fresh green salad. Customize with sun-dried tomatoes or scallions for extra flavor.

Updated on Tue, 20 Jan 2026 14:36:00 GMT
Golden-brown Artichoke Spinach Grilled Cheese slices oozing creamy melted cheese and greens on a plate. Save
Golden-brown Artichoke Spinach Grilled Cheese slices oozing creamy melted cheese and greens on a plate. | munchhug.com

The smell of garlic and melting cheese pulled my roommate out of her room one rainy Thursday. I was experimenting with leftover dip from game night, wondering if I could stuff it into bread and call it dinner. The first sandwich came off the skillet with a crackle, cheese oozing at the edges, and we both stood there with forks, too impatient to sit down. It became our comfort meal that winter, the kind of thing we made when we needed something warm and ridiculous.

I made these for my sister the weekend she moved into her first apartment. We sat on folding chairs surrounded by boxes, eating sandwiches off paper plates, and she said it tasted better than anything she'd cooked for herself in weeks. The artichokes gave it just enough substance to feel like real food, and the spinach made us feel slightly less guilty about eating cheese for lunch. She texted me two days later asking for the proportions because she'd already bought the ingredients again.

Ingredients

  • Fresh spinach: Chop it finely so it blends into the filling without creating stringy bites, or use frozen and squeeze it bone dry to avoid watery filling.
  • Artichoke hearts: Jarred or canned both work, but make sure to drain them well and pat dry with a towel to keep the mixture thick.
  • Cream cheese: Let it sit at room temperature for twenty minutes so it mixes smoothly without lumps.
  • Mozzarella and Monterey Jack: Shred them yourself if possible, pre-shredded bags have anti-caking agents that can make the melt less creamy.
  • Parmesan: Freshly grated adds a sharp, nutty depth that the filling needs for balance.
  • Sourdough bread: The tangy flavor complements the richness of the cheese, and the sturdy structure keeps everything contained.
  • Garlic: One small clove is enough, too much will overpower the artichokes.
  • Red pepper flakes: Optional but they add a subtle warmth that cuts through the creaminess.
  • Butter: Softened butter spreads easily and gives the bread a golden, even crust.

Instructions

Product image
Season soups, salads, meats, and vegetables evenly while cooking with quick, one-handed grinding.
Check price on Amazon
Mix the filling:
Combine cream cheese, mozzarella, Monterey Jack, Parmesan, spinach, artichokes, garlic, black pepper, red pepper flakes, and a pinch of salt in a bowl. Stir until everything is evenly distributed and the mixture looks cohesive, like a thick dip.
Assemble the sandwiches:
Lay out eight slices of sourdough and spread the artichoke-spinach mixture generously onto four slices, then top with the remaining bread. Press down gently so the filling spreads to the edges.
Butter the outside:
Spread softened butter on both outer sides of each sandwich, making sure to cover the corners where bread tends to burn first. This step is what creates that golden, crispy crust.
Grill until golden:
Heat a large skillet or griddle over medium heat and place sandwiches in the pan without crowding. Cook for three to four minutes per side, pressing gently with a spatula, until the bread turns deep golden brown and the cheese inside starts to melt and bubble at the edges.
Rest and serve:
Remove sandwiches from the skillet and let them rest for one minute so the filling sets slightly and doesn't spill out when you cut. Slice in half and serve warm.
Product image
Season soups, salads, meats, and vegetables evenly while cooking with quick, one-handed grinding.
Check price on Amazon
Crusty sourdough Artichoke Spinach Grilled Cheese halves stacked, revealing warm spinach and artichoke dip filling. Save
Crusty sourdough Artichoke Spinach Grilled Cheese halves stacked, revealing warm spinach and artichoke dip filling. | munchhug.com

My friend brought these to a potluck and people kept asking if she'd ordered them from a restaurant. She laughed and said it was just spinach dip with an identity crisis. Someone suggested cutting them into small squares for appetizers, and now that's how I serve them at gatherings. They disappear faster than anything else on the table, and I always keep extra filling in the fridge just in case.

How to Avoid a Soggy Sandwich

The key is controlling moisture before it hits the bread. Thaw frozen spinach completely, then wrap it in a clean kitchen towel and twist hard until no more water drips out. Do the same with the artichokes after draining them. I learned this the hard way when my first batch soaked through the bread and turned into a cheesy puddle in the pan. Now I treat both ingredients like I'm wringing out a washcloth, and the filling stays thick and spreadable.

What to Serve Alongside

These sandwiches are rich, so I like pairing them with something bright and acidic. A simple arugula salad with lemon vinaigrette balances the creaminess, or a cup of tomato soup for dipping if you're feeling nostalgic. I've also served them with pickles and kettle chips when I want something casual and crunchy. The contrast makes each bite feel less heavy, and you can finish a whole sandwich without feeling weighed down.

Make-Ahead and Storage Tips

You can make the filling up to two days ahead and keep it in an airtight container in the fridge. When you're ready to cook, let it sit at room temperature for ten minutes so it spreads easily. I don't recommend assembling the sandwiches in advance because the bread absorbs moisture and won't crisp up as well. If you have leftover cooked sandwiches, reheat them in a skillet over low heat instead of the microwave, which makes the bread chewy.

  • Store filling separately for up to two days to keep bread from getting soggy.
  • Reheat cooked sandwiches in a skillet to restore the crispy crust.
  • Double the filling recipe and freeze half for an easy future meal.
Product image
Prep meals effortlessly by chopping vegetables, slicing meats, and serving dinner with the right knife always ready.
Check price on Amazon
Artichoke Spinach Grilled Cheese sandwich cut on board with tomato soup bowl, fresh greens, and knife. Save
Artichoke Spinach Grilled Cheese sandwich cut on board with tomato soup bowl, fresh greens, and knife. | munchhug.com

This sandwich has become my answer to the question of what to make when I want something comforting but don't want to think too hard. It's messy, satisfying, and tastes like you put in more effort than you actually did.

Recipe Guide

Can I prepare this sandwich ahead of time?

Yes, prepare the spinach-artichoke filling up to 2 days in advance and store in the refrigerator. Assemble and cook the sandwiches fresh when ready to serve for the best texture and melted cheese consistency.

What bread works best for this sandwich?

Sourdough is recommended for its sturdy texture and tangy flavor that complements the creamy filling. You can also use whole wheat bread for added fiber or gluten-free bread for dietary needs.

How do I prevent the bread from burning while melting the cheese?

Use medium heat and cook 3-4 minutes per side, pressing gently. Don't rush the process. If bread browns too quickly, reduce heat slightly to allow cheese to melt thoroughly before the bread becomes too dark.

Can I add other vegetables to the filling?

Absolutely. Sun-dried tomatoes, chopped scallions, caramelized onions, or roasted red peppers work wonderfully. Add them to the cream cheese mixture before spreading on the bread for enhanced flavor.

What cheese substitutes work if I'm dairy-free?

Use dairy-free cream cheese and plant-based mozzarella alternatives. Nutritional yeast adds cheesy flavor depth. Note that melting behavior may differ slightly, so monitor cooking time closely.

Is this sandwich suitable for vegetarians?

Yes, this sandwich is completely vegetarian. It contains no meat products, only cheeses, spinach, artichokes, and sourdough bread, making it an excellent meatless main dish option.

Artichoke Spinach Grilled Cheese

A decadent sandwich with creamy spinach-artichoke filling melted between golden, crisp sourdough bread.

Prep duration
15 min
Heat time
10 min
Complete duration
25 min
Created by Samantha Reed

Type Cozy Eats

Skill level Easy

Heritage American

Output 4 Portions

Nutrition preferences Meat-free

Components

Vegetables

01 1 cup fresh spinach, chopped (or 1/2 cup frozen, thawed and drained)
02 1 cup canned or jarred artichoke hearts, drained and chopped

Dairy

01 4 oz cream cheese, softened
02 1/2 cup shredded mozzarella cheese
03 1/2 cup shredded Monterey Jack or Swiss cheese
04 1/4 cup grated Parmesan cheese
05 2 tablespoons unsalted butter, softened

Bread

01 8 slices sourdough bread

Seasonings

01 1 small garlic clove, minced
02 1/4 teaspoon black pepper
03 1/8 teaspoon crushed red pepper flakes (optional)
04 Pinch of salt

Method

Phase 01

Prepare the filling: In a mixing bowl, combine softened cream cheese, mozzarella, Monterey Jack or Swiss, Parmesan, chopped spinach, drained artichoke hearts, minced garlic, black pepper, red pepper flakes, and salt. Mix until well blended.

Phase 02

Assemble sandwiches: Lay out sourdough slices and spread the artichoke-spinach mixture evenly onto 4 slices. Top with remaining bread slices to form sandwiches.

Phase 03

Butter the exterior: Lightly butter the outside of each sandwich on both sides.

Phase 04

Cook until golden: Heat a large skillet or griddle over medium heat. Place sandwiches in the pan and cook 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Phase 05

Rest and serve: Remove from skillet, let rest 1 minute, then slice and serve warm.

Tools needed

  • Mixing bowl
  • Spoon or spatula
  • Knife and cutting board
  • Skillet or griddle
  • Spatula for flipping

Allergy alerts

Review ingredients carefully for potential allergens and seek professional medical guidance if concerned.
  • Contains dairy (cheese, butter) and wheat (bread)
  • May contain soy depending on bread and cheese brands
  • Check labels for potential cross-contamination if allergies are severe

Dietary info (per portion)

Values shown are estimates only - please consult healthcare providers for specific advice.
  • Energy: 410
  • Lipids: 23 g
  • Carbohydrates: 38 g
  • Proteins: 15 g