Spicy Cajun Chicken Alfredo

Featured in: Global Comforts

This dish features tender chicken breasts generously coated with bold Cajun seasoning and seared to a golden finish. Cooked fettuccine is combined with a silky Alfredo sauce made from butter, garlic, heavy cream, Parmesan, smoked paprika, and optional chili flakes for extra heat. The pasta is gently tossed in the sauce, then topped with sliced chicken and fresh parsley for a balance of creamy textures and smoky, spicy flavors.

Updated on Sat, 15 Nov 2025 10:17:00 GMT
Sizzling Spicy Cajun Chicken Alfredo with creamy sauce, parsley garnish, and tender chicken slices. Save
Sizzling Spicy Cajun Chicken Alfredo with creamy sauce, parsley garnish, and tender chicken slices. | munchhug.com

A bold creamy pasta dish featuring tender Cajun-spiced chicken tossed with fettuccine in a rich Alfredo sauce perfect for spice lovers.

I remember the first time I made this Cajun chicken Alfredo for my friends and everyone was amazed by how perfectly the heat and creaminess balanced in each bite.

Ingredients

  • Boneless skinless chicken breasts: 2 large sliced for even cooking
  • Cajun seasoning: 2 tablespoons for coating chicken generously
  • Olive oil: 1 tablespoon for searing the chicken
  • Fettuccine: 340 g (12 oz) traditional pasta base
  • Unsalted butter: 2 tablespoons creates a rich Alfredo sauce
  • Garlic: 3 cloves minced for aromatic flavor
  • Heavy cream: 1 cup (240 ml) ensures a luscious velvety sauce
  • Parmesan cheese: 1 cup (100 g) freshly grated for best melting
  • Smoked paprika: 1/2 teaspoon adds subtle smokiness
  • Chili flakes: 1/2 teaspoon optional for extra heat
  • Salt and black pepper: to taste adjust seasoning
  • Chopped fresh parsley: 2 tablespoons finishing herb
  • Extra grated Parmesan cheese: for garnish

Instructions

Prepare Pasta:
Cook fettuccine according to package instructions in salted boiling water until al dente. Reserve 1/2 cup pasta water then drain and set aside.
Season Chicken:
Pat chicken breasts dry and coat them evenly with Cajun seasoning for robust flavor.
Cook Chicken:
Heat olive oil in a large skillet over medium-high heat. Add chicken and cook 5 6 minutes per side or until fully cooked and golden brown. Remove chicken let rest for 5 minutes then slice thinly.
Make Alfredo Sauce:
In same skillet reduce heat to medium and add butter. Sauté minced garlic for 1 minute until fragrant.
Finish Sauce:
Stir in heavy cream smoked paprika and chili flakes. Bring to a gentle simmer then whisk in Parmesan cheese until melted and sauce is smooth. Season with salt and pepper.
Combine:
Add cooked fettuccine to sauce tossing to coat. If needed add reserved pasta water a little at a time for a silkier sauce.
Serve:
Top pasta with sliced Cajun chicken. Garnish with chopped parsley and extra Parmesan. Serve immediately.
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This dish is always a hit for family dinners everyone enjoys the savory creamy sauce with a kick of Cajun spice.

Required Tools

Large pot large skillet tongs chefs knife cutting board measuring cups and spoons make prep and cooking smooth.

Allergen Information

Contains dairy and gluten check Cajun seasoning ingredients for possible mustard or celery allergens.

Nutritional Information

Per serving Calories 610 Total Fat 27 g Carbohydrates 54 g Protein 38 g.

Golden-brown Cajun-spiced chicken atop fettuccine in a rich and flavorful Spicy Cajun Chicken Alfredo. Save
Golden-brown Cajun-spiced chicken atop fettuccine in a rich and flavorful Spicy Cajun Chicken Alfredo. | munchhug.com

Enjoy this spicy Cajun chicken Alfredo fresh as soon as it's made. The creamy sauce and bold spice blend make every bite unforgettable.

Recipe Guide

How do you achieve tender chicken in this dish?

Pat the chicken dry and evenly coat with Cajun seasoning before cooking. Sear over medium-high heat for 5-6 minutes per side until golden and cooked through, then let rest to retain juiciness.

Can I substitute the fettuccine with other pasta?

Yes, penne or linguine work well as alternatives, maintaining the sauce's creamy coating and texture.

What adds the smoky flavor to the sauce?

Smoked paprika infuses the Alfredo sauce with a subtle smokiness that complements the Cajun spices.

How can I adjust the spice level?

Increase the amount of Cajun seasoning or add more chili flakes to the sauce for a bolder heat profile.

What is the purpose of reserved pasta water?

Adding reserved pasta water helps loosen the sauce, creating a silkier texture that clings better to the pasta.

Can I lighten the sauce for a less rich dish?

Using half-and-half instead of heavy cream reduces richness while still providing a creamy consistency.

Spicy Cajun Chicken Alfredo

Cajun-seasoned chicken and fettuccine blend in a rich, creamy sauce with garlic and Parmesan cheese.

Prep duration
15 min
Heat time
25 min
Complete duration
40 min
Created by Samantha Reed


Skill level Medium

Heritage American (Cajun-inspired, Italian-American)

Output 4 Portions

Nutrition preferences None specified

Components

Chicken

01 2 large boneless, skinless chicken breasts
02 2 tablespoons Cajun seasoning
03 1 tablespoon olive oil

Pasta

01 12 ounces fettuccine

Alfredo Sauce

01 2 tablespoons unsalted butter
02 3 cloves garlic, minced
03 1 cup heavy cream
04 1 cup freshly grated Parmesan cheese
05 1/2 teaspoon smoked paprika
06 1/2 teaspoon chili flakes (optional)
07 Salt and black pepper, to taste

Garnishes

01 2 tablespoons chopped fresh parsley
02 Extra grated Parmesan cheese

Method

Phase 01

Cook Pasta: Boil salted water and cook fettuccine until al dente, reserving 1/2 cup pasta water. Drain and set aside.

Phase 02

Prepare Chicken: Pat chicken breasts dry and evenly coat with Cajun seasoning.

Phase 03

Sear Chicken: Heat olive oil in a large skillet over medium-high heat, cook chicken 5-6 minutes per side until cooked through and golden. Remove and let rest for 5 minutes, then slice thinly.

Phase 04

Make Alfredo Sauce: Reduce heat to medium and melt butter in the same skillet. Sauté minced garlic for 1 minute until fragrant.

Phase 05

Simmer Sauce: Stir in heavy cream, smoked paprika, and chili flakes, bringing to a gentle simmer. Whisk in Parmesan cheese until fully melted and smooth. Season with salt and black pepper.

Phase 06

Combine Pasta and Sauce: Toss cooked fettuccine in sauce, adding reserved pasta water incrementally to achieve desired sauce consistency.

Phase 07

Assemble Dish: Plate pasta, top with sliced Cajun chicken, and garnish with chopped parsley and additional Parmesan cheese. Serve immediately.

Tools needed

  • Large pot
  • Large skillet
  • Tongs
  • Chef's knife
  • Cutting board
  • Measuring cups and spoons

Allergy alerts

Review ingredients carefully for potential allergens and seek professional medical guidance if concerned.
  • Contains dairy (cream, butter, Parmesan)
  • Contains gluten (fettuccine)
  • May contain allergens from Cajun seasoning such as mustard or celery

Dietary info (per portion)

Values shown are estimates only - please consult healthcare providers for specific advice.
  • Energy: 610
  • Lipids: 27 g
  • Carbohydrates: 54 g
  • Proteins: 38 g